High Throughput Oligo Synthesizer With Negative Pressure Waste Discharge System

The HY-192 DNA RNA Synthesizer can be operated in both R&D and high-throughput production facilities, with the ability to utilize synthesis plates or individual columns, making it the most versatile high-throughput DNA/RNA oligo synthesizer yet. More reagents create more opportunities to push your experiments to the next level. The HY-192 is equipped with the most reagents we have ever put in a high throughput oligo synthesizer. Synthesize anywhere from 1 to 192 oligos using up to 37 total reagents and up to a 1 umol scale.

1. Each reagent is an independent channel from the liquid storage bottle to the synthesis column without other channels cross.
2. The activator and Phosphoramidite are added sequentially during the coupling process and premixed on the synthesis column to carry out the reaction.
3. It is equipped with two plates with a total of 192 synthesis columns and 12-20 base bottle ports.
4. In addition to 4 standard bases and synthetic auxiliary reagents, there are also 8 modified bases, which can be synthesized as required, such as thiomodification, or other fluorescent modifications and double-labeled TAQMAN probes, etc. More than 8 special bases.
5. It has automatic synthesis and consolidation of bases without the need for pre-mixing of Phosphoramidites.
6. During the whole process of synthesis, there is a certain amount in the synthesis chamber (the amount of gas can be adjusted) The protective gas is filled to prevent air from entering the synthesis cavity and affect the synthesis quality.
7. Reagents and Phosphoramidite can be loaded into two bottles at one time, which can effectively increase the time of single synthesis without frequent replacement of reagents.
8. Equipped with a cleaning switch valve, and acetonitrile and argon can be used to flush pipelines and valves to avoid blockage of pipelines and valves caused by long-term idling of the equipment.
9. The equipment has the functions of self-checking and protection, power-off, suspend and continue.
10. Working conditions and safety requirements conform to relevant Chinese and international standards or regulations.